Open Access<p>Circ_0058124 Aggravates the Progression of Papillary Thyroid Carcinoma by Activating LMO4 Expression via Targeting miR-370-3p</p>
Author(s) -
Lei Liu,
Chaohui Yan,
Shudong Tao,
Hailin Wang
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
ISSN - 1179-1322
DOI - 10.2147/cmar.s271778
Subject(s) - gene knockdown , cancer research , thyroid cancer , apoptosis , thyroid carcinoma , cell growth , flow cytometry , viability assay , cell culture , chemistry , in vivo , cell migration , cell , biology , medicine , cancer , microbiology and biotechnology , thyroid , biochemistry , genetics
Thyroid cancer is the most common malignant tumor in the endocrine system. Papillary thyroid carcinoma (PTC) accounts for the vast majority of cases in this cancer. Recently, the vital role of circular RNA (circRNA) has been acknowledged in various cancers, and this study aimed to investigate the role of circ_0058124 and related mechanism of its action in PTC.