Open Access<p>Oridonin Induces Apoptosis of Laryngeal Carcinoma via Endoplasmic Reticulum Stress</p>
Author(s) -
Bo Kou,
Yang Yang,
Yin-E Bai,
Yuhan Shi,
Ruixia Gao,
Fangli Yang,
Shaoqiang Zhang,
Wei Liu
Publication year - 2020
Publication title -
cancer management and research
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s271759
Subject(s) - apoptosis , mtt assay , cancer research , western blot , flow cytometry , blot , unfolded protein response , chemistry , endoplasmic reticulum , medicine , biology , microbiology and biotechnology , biochemistry , gene
Oridonin, a bioactive diterpenoid derived from Rabdosia rubescens , has been widely reported to exhibit anticancer activity in multiple types of cancer. However, the molecular mechanism of oridonin in human laryngeal carcinoma has not been clearly elucidated. This study investigated the function of oridonin in laryngeal carcinoma to provide a research basis for laryngeal carcinoma therapy.