
<p>Effect of miR-515-5p on Proliferation and Drug Sensitivity of Retinoblastoma Cells</p>
Author(s) -
Xiang Wen Yuan,
Ting Yan,
Huilin Tong
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s271165
Subject(s) - retinoblastoma , cell growth , microrna , downregulation and upregulation , cell culture , cancer research , chemistry , in vitro , cell , retinoblastoma protein , drug , in vivo , microbiology and biotechnology , biology , cell cycle , pharmacology , gene , biochemistry , genetics
Retinoblastoma (RB) is a common malignancy in children eyes. Aberrant microRNA (miR) expression is observed in many cancer cases. miR-515-5p is reported to be concerned with the course of many cancers. This study explores the role of miR-515-5p in proliferation and drug sensitivity of RB cells.