Open Access<p>Down-Regulation of Circ_0032833 Sensitizes Colorectal Cancer to 5-Fluorouracil and Oxaliplatin Partly Depending on the Regulation of miR-125-5p and MSI1</p>
Author(s) -
Shouchao Li,
Shu Zheng
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s270123
Subject(s) - oxaliplatin , folfox , gene knockdown , colorectal cancer , cancer research , chemistry , fluorouracil , flow cytometry , apoptosis , in vivo , microbiology and biotechnology , medicine , cancer , biology , biochemistry
5-fluorouracil, leucovorin, and oxaliplatin (FOLFOX) is an effective chemotherapy for colorectal cancer (CRC) in clinic. It remains unclear regarding the effect of circular RNA (circRNA) circ_0032833 on regulating chemosensitivity in CRC.