Open Access<p>Depth of Response and Early Tumor Shrinkage for Predicting Clinical Outcomes in HER2-Positive Metastatic Breast Cancer Treated with Trastuzumab</p>
Author(s) -
YiQun Che,
Yue Zhang,
Kaiping Ou,
Di Wang,
Di Shen,
Huiying Liu,
Yang Luo
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s269067
Subject(s) - medicine , trastuzumab , hazard ratio , proportional hazards model , oncology , breast cancer , confidence interval , cutoff , metastatic breast cancer , multivariate analysis , cancer , youden's j statistic , gastroenterology , receiver operating characteristic , physics , quantum mechanics
To evaluate whether the depth of response (DepRe) and early tumor shrinkage (ETS) are predictive factors of clinical outcomes in HER2-positive metastatic breast cancer (mBC) patients treated with trastuzumab.