Open Access<p>MCM10 Acts as a Potential Prognostic Biomarker and Promotes Cell Proliferation in Hepatocellular Carcinoma: Integrated Bioinformatics Analysis and Experimental Validation</p>
Author(s) -
Wei Keat Wan,
Yun Shen,
Quanxi Li
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s267493
Subject(s) - kegg , cell cycle , cancer research , hepatocellular carcinoma , gene knockdown , gene , biology , cell growth , wnt signaling pathway , gene expression , bioinformatics , oncology , medicine , genetics , gene ontology
Hepatocellular carcinoma (HCC) is one of the most common human malignant tumors. The prognosis of HCC patients is still unsatisfying. Thus, it is of great importance to identify novel molecules and functional pathways associated with the pathophysiology of HCC. In this study, we performed the integrated bioinformatics analysis and experiment validation to identify novel biomarkers in the prognosis and progression of HCC.