Open AccessmicroR-4449 Promotes Colorectal Cancer Cell Proliferation via Regulation of SOCS3 and Activation of STAT3 Signaling
Author(s) -
Zhaowei Yan,
Sen Hong,
Yumei Song,
Miaomiao Bi
Publication year - 2021
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s266153
Subject(s) - stat3 , socs3 , microrna , cell growth , cancer research , colorectal cancer , downregulation and upregulation , apoptosis , signal transduction , chemistry , stat protein , microarray analysis techniques , microbiology and biotechnology , biology , gene expression , cancer , gene , biochemistry , genetics
Dysregulation of microRNAs (miRNAs), which represented a critical level of gene expression modulation, regulated the development of colorectal cancer. However, the functions of numerous miRNAs remain unclear in colorectal cancer.