Open Access<p>Elevated Expression of ASXL2 is Associated with Poor Prognosis in Colorectal Cancer by Enhancing Tumorigenesis and Inducing Cell Proliferation</p>
Author(s) -
Ran Cui,
Luwei Yang,
Yiwei Wang,
Ming Zhong,
Minhao Yu,
Bin Chen
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
ISSN - 1179-1322
DOI - 10.2147/cmar.s266083
Subject(s) - colorectal cancer , carcinogenesis , cancer research , cell growth , real time polymerase chain reaction , cancer , downregulation and upregulation , biology , immunohistochemistry , western blot , transfection , medicine , cell culture , immunology , gene , genetics
Colorectal cancer is one of the most common malignant tumors worldwide. ASXL2 is an enhancer of the trithorax and polycomb genes, which have been proven to act in many tumor types. The role of ASXL2 in the occurrence and development of tumors has been extensively studied in recent years. However, the relationship between ASXL2 and the prognosis of CRC is still unclear.