Open Access<p>Value of Ultrasound Combined with Immunohistochemistry Evaluation of Central Lymph Node Metastasis for the Prognosis of Papillary Thyroid Carcinoma</p>
Author(s) -
Xiaohua Yao,
Ying Meng,
Runsheng Guo,
Guofeng Lu,
Jia Wei Lin,
Yingchun Wang,
De-Bin Yang
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s265756
Subject(s) - medicine , stage (stratigraphy) , thyroid carcinoma , immunohistochemistry , thyroid cancer , lymph node , oncology , t stage , proportional hazards model , ultrasound , cancer , radiology , thyroid , paleontology , biology
Papillary thyroid carcinoma (PTC) is often accompanied by cervical lymph node metastasis (LNM). The accuracy of the preoperative ultrasound diagnosis of central LNM (CLNM) is limited. LNM is a high-risk factor for local recurrence and may affect the prognosis. Factors not directly related to tumor proliferation are used for risk assessment in the tumor-node-metastasis (TNM) staging system for thyroid cancer. The present study aimed to investigate the value of ultrasound and immunohistochemistry in predicting the presence of CLNM and the prognosis of PTC.