Open Access<p>CircPVT1 Promoted the Progression of Breast Cancer by Regulating MiR-29a-3p-Mediated AGR2-HIF-1α Pathway</p>
Author(s) -
Jing Wang,
Kuo Chin Huang,
Lang Shi,
Qingyong Zhang,
Shengchu Zhang
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s265579
Subject(s) - apoptosis , mcf 7 , cell growth , downregulation and upregulation , cell , cancer research , biology , cancer cell , microrna , cell culture , western blot , cancer , microbiology and biotechnology , chemistry , gene , human breast , genetics
Breast cancer (BC) is a great contributor to cancer-related death. Mounting studies have identified that circular RNAs (circRNAs) play vital roles in cancer cell proliferation, apoptosis and invasion. Here, we explored the effect of circPVT1 on BC development as well as its downstream mechanisms.