Open Access<p>CREB1 Suppresses Transcription of microRNA-186 to Promote Growth, Invasion and Epithelial–Mesenchymal Transition of Gastric Cancer Cells Through the KRT8/HIF-1α Axis</p>
Author(s) -
Xue Huang,
Fujian Liu,
ZhiYong Jiang,
Hang Guan,
Qiu-Hong Jia
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s265187
Subject(s) - gene silencing , creb1 , downregulation and upregulation , microrna , epithelial–mesenchymal transition , microbiology and biotechnology , chemistry , biology , transcription factor , biochemistry , creb , gene
The cAMP response element-binding protein 1 (CREB1) was initiated as a potential target for cancer treatment. This research was conducted to probe the effect of CREB1 in the progression of gastric cancer (GC) and the molecules involved.