Open Access<p>PACE4 Expression is a Novel Independent Prognostic Factor in Nasopharyngeal Carcinoma</p>
Author(s) -
Yingsong Lin,
Huidong Long,
Xin Tan,
Donghui Zhang,
Liwen Jiang
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s264143
Subject(s) - immunohistochemistry , nasopharyngeal carcinoma , biomarker , medicine , cancer , metastasis , tumor progression , pathology , oncology , biology , radiation therapy , biochemistry
Paired basic amino acid-cleaving enzyme 4 (PACE4) belongs to the family of proprotein convertase and is essential for tumor progression, whereas its role in cancer remains controversial and little is known about its role in nasopharyngeal carcinoma (NPC). The aim of this study was to examine if the expression of PACE4 is a prognostic biomarker for patients with NPC.