Open Access<p>Ursolic Acid Protects Against Proliferation and Inflammatory Response in LPS-Treated Gastric Tumour Model and Cells by Inhibiting NLRP3 Inflammasome Activation</p>
Author(s) -
Zixi Chen,
Qiaoli Liu,
Zhaowei Zhu,
Fenfen Xiang,
Mengzhe Zhang,
Rong Wu,
Xin Kang
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s264070
Subject(s) - ursolic acid , inflammasome , lipopolysaccharide , chemistry , inflammation , pharmacology , nf κb , cancer research , cancer , cell culture , cancer cell , apoptosis , biochemistry , medicine , immunology , biology , chromatography , genetics
Inflammation is considered as one of the hallmarks of cancer development and progression. Ursolic acid (UA) showed strong effects as an anti-inflammatory and antioxidant. However, the anti-cancer effects of ursolic acid require further study.