Open Access
<p>Ultrasound-Targeted Microbubble Destruction Mediated si-CyclinD1 Inhibits the Development of Hepatocellular Carcinoma via Suppression of PI3K/AKT Signaling Pathway</p>
Author(s) -
Wei Yan,
Li Cheng,
Dongmei Zhang
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s263590
Subject(s) - cyclin d1 , pi3k/akt/mtor pathway , protein kinase b , apoptosis , cancer research , cell growth , flow cytometry , hepatocellular carcinoma , in vivo , signal transduction , western blot , chemistry , microbiology and biotechnology , biology , cell cycle , biochemistry , gene
In our study, we aimed to investigate the effect of ultrasound-targeted microbubble destruction (UTMD)mediated si-CyclinD1 (CCND1) on the growth of hepatocellular carcinoma (HCC) cells.