Open Access<p>LncRNA MALAT1 Aggravates the Progression of Non-Small Cell Lung Cancer by Stimulating the Expression of COMMD8 via Targeting miR-613</p>
Author(s) -
Wang Shouzhong,
Tao Wang,
Darui Liu,
H. S. Kong
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s263538
Subject(s) - malat1 , cancer research , cell growth , lactate dehydrogenase a , gene knockdown , apoptosis , cell cycle , biology , flow cytometry , microbiology and biotechnology , microrna , cell , chemistry , lactate dehydrogenase , downregulation and upregulation , long non coding rna , biochemistry , gene , enzyme
Non-small cell lung cancer (NSCLC) is a common malignant tumor in humans. Long non-coding RNA (lncRNA) involved in cancer progression has been reported frequently. The objective of this study was to investigate the role of lncRNA metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) and explore a novel mechanism in NSCLC development.