Open Access<p>LncRNA PVT1 Regulates TRPS1 Expression in Breast Cancer by Sponging miR-543</p>
Author(s) -
Hongtao Wang,
YuanLi Huang,
Yuanrong Yang
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s263383
Subject(s) - pvt1 , cancer research , medicine , breast cancer , oncology , biology , long non coding rna , cancer , downregulation and upregulation , genetics , gene
Breast cancer is the most common female malignancy with high invasion and metastasis abilities. Studies have shown that long non-coding RNA (lncRNA) plasmacytoma variant translocation 1 gene (PVT1) is an oncogene and is positively correlated with progression and metastasis of breast tumors. However, the detailed mechanism of PVT1 in breast cancer tumorigenesis is not fully understood.