Open AccessHNRNPCL1, PRAMEF1, CFAP74, and DFFB: Common Potential Biomarkers for Sporadic and Suspected Lynch Syndrome Endometrial Cancer
Author(s) -
Yuan Gao,
Xiuping Zhang,
Tian Wang,
Ye Zhang,
Qingxuan Wang,
Y. Hu
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s262421
Subject(s) - mlh1 , msh6 , pms2 , lynch syndrome , msh2 , exome sequencing , genetics , endometrial cancer , biology , population , exome , mutation , oncology , medicine , cancer , gene , dna mismatch repair , germline mutation , colorectal cancer , environmental health
To investigate the genes of patients with sporadic endometrial cancer (EC) and suspected Lynch syndrome (LS)-related EC in the Chinese population. Identification of meaningful mutation sites can provide theoretical basis for molecular targeted therapy, aiming to improve the prognosis of patients with EC.