Open Access<p>EGLIF-CAR-T Cells Secreting PD-1 Blocking Antibodies Significantly Mediate the Elimination of Gastric Cancer</p>
Author(s) -
Jingtao Zhou,
Jiang-Hao Liu,
Tingting Song,
Marinus A. Blankenstein,
Nuermaimait Amidula,
Chunmei Bai
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s260915
Subject(s) - chimeric antigen receptor , cancer research , antibody , cancer immunotherapy , cancer cell , autocrine signalling , cancer , antigen , immunotherapy , in vitro , chemistry , receptor , immune system , medicine , immunology , biochemistry
To investigate the anti-tumor effects of programmed cell death protein 1 (PD-1) scFv-secreting EGFR-chimeric antigen receptor-modified (CAR)-T cells against gastric cancer.