Open Access<p>Plasmacytoid Dendritic Cell Infiltration in Acute Myeloid Leukemia</p>
Author(s) -
Lifei Zhu,
Ping Wang,
Wei Zhang,
Qiong Li,
Jingkang Xiong,
Jiali Li,
Xiao-Chen Deng,
Yao Liu,
Chao Yang,
Peiyan Kong,
Xiaotong Peng,
Jiang Zhong,
Jun Rao,
Xi Zhang
Publication year - 2020
Publication title -
cancer management and research
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s260825
Subject(s) - infiltration (hvac) , medicine , myeloid leukemia , leukemia , bone marrow , chronic myelomonocytic leukemia , cancer research , chemotherapy , tumor microenvironment , myeloid , flow cytometry , pathology , oncology , immunology , cancer , myelodysplastic syndromes , physics , thermodynamics
Increasing evidence has demonstrated that plasmacytoid dendritic cells (PDCs) in the tumor microenvironment (TME) play an important role in tumorigenesis and progression. PDC infiltration has been found in certain malignancies such as classic Hodgkin's lymphoma and chronic myelomonocytic leukemia. Our previous work reported that PDC infiltration could occur in acute myeloid leukemia (AML), but the clinical significance of PDC in AML has not been thoroughly investigated.