Open Access<p>Curcumin Modifies Epithelial–Mesenchymal Transition in Colorectal Cancer Through Regulation of miR-200c/EPM5</p>
Author(s) -
Hui Wang,
Xi Cai,
Likun Ma
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s260129
Subject(s) - curcumin , downregulation and upregulation , gene knockdown , epithelial–mesenchymal transition , microrna , cancer research , ectopic expression , colorectal cancer , western blot , cancer , chemistry , biology , medicine , oncology , cell culture , pharmacology , gene , biochemistry , genetics
The serious side effect of current conventional treatments for patients with metastatic colorectal cancer (CRC) highlights the requirement of an alternative treatment strategy. Natural compounds, such as curcumin, have been gained much attention due to its low toxicity and anti-tumor effect.