Open Access<p>Prognostic Significance of Rab27A and Rab27B Expression in Esophageal Squamous Cell Cancer</p>
Author(s) -
Fengqiang Yu,
Weihan Wu,
Mingqiang Liang,
Yu Huang,
Chun Chen
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s258940
Subject(s) - rab , clinical significance , stage (stratigraphy) , medicine , cancer , immunohistochemistry , oncology , cancer research , biology , gtpase , microbiology and biotechnology , paleontology
Rab27A and Rab27B, members of the Rab family of small GTPases, have aberrant expression and exert different roles in various cancers. However, their expression and potential prognostic values in esophageal squamous cell cancer (ESCC) still remain elusive. In the present study, we explored the association of Rab27A and Rab27B expression with clinical significance and prognosis in ESCC.