Open Access<p><em>ONECUT2</em> Accelerates Tumor Proliferation Through Activating <em>ROCK1</em> Expression in Gastric Cancer</p>
Author(s) -
Jie Chen,
Jinggui Chen,
Bo Sun,
Jianghong Wu,
Chunyan Du
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s256316
Subject(s) - gene knockdown , wnt signaling pathway , cell growth , kegg , biology , cell cycle , microbiology and biotechnology , cancer research , carcinogenesis , rock1 , apoptosis , cancer , signal transduction , gene expression , gene , genetics , rhoa , transcriptome
Transcription factors (TFs) are key regulators which control gene expression during cancer initiation and progression. In the current study, we aimed to explore the proliferative function and clinical significance of TFs in gastric cancer (GC).