Open Access<p>Long Intergenic Non-Protein Coding RNA 1094 Promotes Initiation and Progression of Glioblastoma by Promoting microRNA-577-Regulated Stabilization of Brain-Derived Neurotrophic Factor</p>
Author(s) -
Xiaoyan Dong,
Xiuxin Fu,
Miao Yu,
Zengfen Li
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
ISSN - 1179-1322
DOI - 10.2147/cmar.s256147
Subject(s) - cancer research , microrna , cell growth , biology , flow cytometry , brain derived neurotrophic factor , glioma , neurotrophic factors , in vivo , apoptosis , cell , long non coding rna , microbiology and biotechnology , rna , gene , receptor , genetics , biochemistry
The long intergenic non-protein coding RNA 1094 (LINC01094) plays a vital role in the oncogenicity of clear cell renal cell carcinoma. However, its expression profile and detailed roles in glioblastoma (GBM) remain unknown. In this study, we mainly investigated the expression and roles of LINC01094 in GBM and focused on the mechanism by which LINC01094 regulates the malignant characteristics of GBM.