Open Access<p>Upregulated SET Promotes Cell Survival Through Activating Akt/NF-κB Signal in Colorectal Carcinoma</p>
Author(s) -
Jianjun Zhu,
Lihong Shi,
Genlai Du,
Li Li,
Ming Liu
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s255930
Subject(s) - gene knockdown , protein kinase b , cancer research , cell growth , cyclin d1 , pi3k/akt/mtor pathway , viability assay , oncogene , apoptosis , cell cycle , biology , small interfering rna , chemistry , signal transduction , microbiology and biotechnology , transfection , cell culture , biochemistry , genetics
SET has been proven to be an oncogene, which promotes the initiation and progression in several kinds of malignant carcinomas. However, the expression and its functional roles in colorectal carcinoma (CRC) remained unknown.