Open AccessTGIF1 Knockdown Inhibits the Proliferation and Invasion of Gastric Cancer via AKT Signaling Pathway
Author(s) -
Jing Zhang,
Feiyan Zhang,
Jia Fan,
Bin Feng
Publication year - 2021
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s254348
Subject(s) - gene knockdown , protein kinase b , cancer research , cell growth , pi3k/akt/mtor pathway , apoptosis , signal transduction , cancer cell , flow cytometry , blot , chemistry , cancer , biology , microbiology and biotechnology , biochemistry , gene , genetics
Gastric cancer is a kind of cancer with high mortality. TGIF1, as a transcription inhibitor, can inhibit the transcription of specific genes. The purpose of this study was to investigate the role of TGIF1 in gastric cancer by knocking down TGIF1.