Open Access<p>Estrogen-Induced Stromal FGF18 Promotes Proliferation and Invasion of Endometrial Carcinoma Cells Through ERK and Akt Signaling</p>
Author(s) -
Jian Wu,
Xiang Tao,
Hong Zhang,
Xianghua Yi,
Yinhua Yu
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s254242
Subject(s) - stromal cell , fibroblast growth factor , protein kinase b , cancer research , mapk/erk pathway , gene knockdown , biology , microbiology and biotechnology , medicine , signal transduction , cell culture , receptor , genetics
The aim of this study was to evaluate whether estrogen promoted the proliferation and invasion of endometrial carcinoma (EC) cells through paracrine FGFs in endometrial stromal cells (ESCs).