Open Access<p>MiR-301a Promotes Cell Proliferation by Repressing PTEN in Renal Cell Carcinoma</p>
Author(s) -
Jun Li,
Donggen Jiang,
Qian Zhang,
Shubin Peng,
Guolong Liao,
Xiangwei Yang,
Jiani Tang,
Haiyun Xiong,
Jun Pang
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s253533
Subject(s) - cancer research , pten , cell growth , gene knockdown , clear cell renal cell carcinoma , biology , cell culture , microrna , flow cytometry , cell , cell cycle , pi3k/akt/mtor pathway , renal cell carcinoma , medicine , signal transduction , oncology , microbiology and biotechnology , gene , biochemistry , genetics
Renal cell carcinoma (RCC) displays an increasing incidence and mortality rate worldwide in recent years. More and more evidence demonstrated microRNAs function as positive or negative regulatory factors in many cancers, while the role of miR-301a in RCC is still unclear.