Open Access<p>MicroRNA-379-5p/YBX1 Axis Regulates Cellular EMT to Suppress Migration and Invasion of Nasopharyngeal Carcinoma Cells</p>
Author(s) -
Fei Zhang,
Duan Chuanxin,
Shucheng Yin,
Ying Tian
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s253504
Subject(s) - nasopharyngeal carcinoma , microrna , epithelial–mesenchymal transition , cell migration , western blot , cancer research , gentamicin protection assay , cell culture , biology , metastasis , reporter gene , cell , gene expression , medicine , cancer , gene , radiation therapy , genetics
Epithelial-mesenchymal transition (EMT) is a major actor modulating the metastasis of nasopharyngeal carcinoma (NPC). Increasing evidence indicates that microRNAs (miRs) are the important regulators of EMT program. However, the potential roles and underlying mechanisms of miR‑379-5p in regulating EMT of NPC cells remain unclear.