Open Access<p>Hypermethylation of the <em>IRAK3</em>-Activated MAPK Signaling Pathway to Promote the Development of Glioma</p>
Author(s) -
Xiaoyun Wu,
Yan Ouyang,
Bin Wang,
Jian Lin,
Yun Bai
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s252772
Subject(s) - glioma , dna methylation , methylation , microbiology and biotechnology , cancer research , biology , mapk/erk pathway , flow cytometry , apoptosis , dna demethylation , viability assay , signal transduction , chemistry , gene expression , gene , biochemistry
This study aimed to elucidate the molecular mechanism underlying the involvement of abnormal DNA methylation in the development of glioma and identify potential new targets for glioma therapy.