Open Access<p>lncRNA PCBP1-AS1 Aggravates the Progression of Hepatocellular Carcinoma via Regulating PCBP1/PRL-3/AKT Pathway</p>
Author(s) -
Tianping Luo,
Yuan Gao,
Guangyan Zhangyuan,
Xiaoliang Xu,
Cailin Xue,
LJ Jin,
Wenjie Zhang,
Chen Zhu,
Beicheng Sun,
Xihu Qin
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s249657
Subject(s) - hepatocellular carcinoma , protein kinase b , cancer research , pi3k/akt/mtor pathway , metastasis , biology , signal transduction , medicine , cancer , microbiology and biotechnology
Hepatocellular carcinoma (HCC) is a very belligerent primary liver tumor with high metastatic potential. Aberrant expression of lncRNAs drives tumorous invasion and metastasis. Whether lncRNAs engage mechanisms of liver cancer metastasis remains largely unexplored.