Open Access<p>Long Non-Coding RNA TTN-AS1 Serves as a Competing Endogenous RNA of miR-195 to Facilitate Clear Cell Renal Cell Carcinoma Progression</p>
Author(s) -
Keng Mean Lin,
Hao Chen,
Chunyan Su,
Huanjin Zhu,
Changchun Lai,
Yaling Shi
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s249456
Subject(s) - clear cell renal cell carcinoma , cyclin d1 , cancer research , competing endogenous rna , gene knockdown , cell growth , biology , cell cycle , long non coding rna , cell culture , cell , microbiology and biotechnology , renal cell carcinoma , rna , medicine , oncology , gene , biochemistry , genetics
Clear cell renal cell carcinoma (ccRCC) is an aggressive human malignancy. Long non-coding RNAs (lncRNAs) are critical regulators in many malignant tumors, including ccRCC. The aim of this study is to investigate the expression, functions and molecular mechanisms of lncRNA TTN-AS1 in ccRCC.