Open Access<p>Predictive Factors for Level V Lymph Node Metastases in Papillary Thyroid Carcinoma with <em>BRAF</em><sup>V600E</sup> Mutation and Clinicopathological Features</p>
Author(s) -
Guiyou Li,
Hai-Long Tan,
Pei Chen,
Hui-Yu Hu,
Mian Liu,
Dengjie Ouyang,
Rooh-Afza Khushbu,
Deepak Pun,
Jindong Li,
Zhipeng Zhang,
Qiong Yang,
Peng Huang,
Chao Shi
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
ISSN - 1179-1322
DOI - 10.2147/cmar.s247914
Subject(s) - medicine , thyroid carcinoma , univariate analysis , neck dissection , lymph node , multivariate analysis , gastroenterology , thyroiditis , odds ratio , thyroidectomy , dissection (medical) , oncology , thyroid , carcinoma , radiology
Therapeutic lateral neck dissection (LND) is recommended in papillary thyroid carcinoma (PTC) patients with clinically lateral lymph node metastasis (LLNM), whether underwent level V LND remains controversial for lacking of sensitive predicting system. BRAF V600E mutation is associated with aggressive tumor behavior, recurrence, and disease-specific mortality of PTC. However, the relationship between BRAF V600E mutation and level V LNM is unclear.