Open Access<p>DNA Methylation in <em>RAR</em>β Gene as a Mediator of the Association Between Healthy Lifestyle and Breast Cancer: A Case–Control Study</p>
Author(s) -
Xuan Wang,
Yupeng Liu,
Hongru Sun,
Anqi Ge,
Dapeng Li,
Jinming Fu,
Yan Li,
Da Pang,
Yong Zhao
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s244606
Subject(s) - mediation , methylation , dna methylation , epigenetics , body mass index , medicine , retinoic acid receptor , breast cancer , endocrinology , retinoic acid , cancer , biology , gene , genetics , gene expression , political science , law
Lifestyle factors and methylation in the retinoic acid receptor β ( RARβ ) gene are associated with breast cancer (BC). This study aims to examine the mediation effect of RARβ methylation on the association between healthy lifestyle and BC in Chinese women.