Open Access<p>LncRNA MALAT1 Regulates the Cell Proliferation and Cisplatin Resistance in Gastric Cancer via PI3K/AKT Pathway</p>
Author(s) -
Qinggang Dai,
Tianqi Zhang,
Chen Li
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s243796
Subject(s) - malat1 , gene knockdown , pi3k/akt/mtor pathway , cancer research , protein kinase b , gentamicin protection assay , cell growth , oncogene , western blot , cancer , biology , apoptosis , microbiology and biotechnology , downregulation and upregulation , cisplatin , chemistry , cell cycle , long non coding rna , gene , biochemistry , genetics , chemotherapy
Many studies showed that long non-coding RNA MALAT1 is served as an oncogene. However, the specific role of MALAT1 in gastric cancer is not fully elucidated. The aim of this study is to elucidate the regulatory effects of MALAT1 on tumor development and cisplatin resistance in gastric cancer.