Open Access<p>Gene Expression Signature to Predict Prognosis and Adjuvant Chemosensitivity of Colorectal Cancer Patients</p>
Author(s) -
Jianxia Li,
Jianwei Zhang,
Huabin Hu,
Yue Cai,
Jiayu Ling,
Zehua Wu,
Yanhong Deng
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s243490
Subject(s) - colorectal cancer , hazard ratio , oncology , medicine , gene signature , proportional hazards model , microarray , adjuvant chemotherapy , stage (stratigraphy) , confidence interval , microarray analysis techniques , gene expression profiling , cancer , gene expression , gene , biology , breast cancer , paleontology , biochemistry
Molecular characteristics using gene-expression profiling can undoubtedly improve the prediction of treatment responses, and ultimately, the clinical outcome of cancer patients. We aimed at developing a genetic signature to improve the prediction of chemosensitivity and prognosis of patients with colorectal cancer (CRC).