Open Access<p>SP1-Induced Upregulation of lncRNA LINC00514 Promotes Tumor Proliferation and Metastasis in Osteosarcoma by Regulating miR-708</p>
Author(s) -
LiDong Mi,
ChuanXiu Sun,
ShengWei He,
Guangyu Du
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s242464
Subject(s) - downregulation and upregulation , chromatin immunoprecipitation , gene silencing , cancer research , osteosarcoma , metastasis , competing endogenous rna , cell growth , oncogene , biology , microrna , long non coding rna , cell , cancer , cell cycle , gene expression , promoter , gene , genetics
Growing studies have suggested the dysregulation of long non-coding RNAs (lncRNAs) in several tumors, including osteosarcoma (OS). However, limited studies report metastasis-associated lncRNAs in OS. Our present study aimed to explore the roles of lncRNA LINC00514 (LINC00514) in OS.