Open Access<p>MicroRNA-155 Suppresses the Translation of p38 and Impairs the Functioning of Dendritic Cells in Endometrial Cancer Mice</p>
Author(s) -
Jianjun Jia,
Xiaomao Li,
Suiqun Guo,
Xingmei Xie
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s240926
Subject(s) - dendritic cell , p38 mitogen activated protein kinases , transfection , cancer research , immune system , microrna , endometrial cancer , biology , microbiology and biotechnology , cancer , cell culture , immunology , signal transduction , mapk/erk pathway , gene , biochemistry , genetics
Dendritic cells (DCs) are reported to play an important role in activating the anti-tumor immune responses. p38 MAPK14 signaling plays an important role in controlling their activity. Here, we identified that miR-155 suppressed the translation of p38 and impaired the functioning of dendritic cells in endometrial cancer.