Open Access<p>Diosmetin Inhibits Cell Proliferation, Induces Cell Apoptosis and Cell Cycle Arrest in Liver Cancer</p>
Author(s) -
Aiqing Ma,
Rui Zhang
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s240064
Subject(s) - cell cycle , cyclin dependent kinase 1 , apoptosis , cell cycle checkpoint , cell growth , checkpoint kinase 2 , transfection , microbiology and biotechnology , chek1 , viability assay , cell , biology , mtt assay , chemistry , cancer research , cell culture , biochemistry , genetics
Diosmetin (DIOS) has been confirmed to possess anti-cancer effects in some types of tumors. However, it remains unclear whether DIOS exerts anti-cancer effects on liver cancer. Thus, our purpose was to observe the effect of DIOS on cell proliferation, cell apoptosis and cell cycle arrest in human liver cancer cells.