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The presence of circulating plasma cells (cPCs) was associated with a worse prognosis in multiple myeloma patients. However, the underlying mechanisms involved in the migration and invasion of bone marrow myeloma cells (BMMCs) to cPCs remains unclear. Here, we investigate the possible factors related to hematogenous myeloma cell dissemination and potential regulatory mechanisms.

<p><em>S1PR2</em> Knockdown Promotes Migration and Invasion in Multiple Myeloma Cells via NF-κB Activation</p>