Open Access<p>OTUD4: A Potential Prognosis Biomarker for Multiple Human Cancers</p>
Author(s) -
Xiaohui Zhao,
Xiaobo Su,
Lu Cao,
Tian Xie,
Quan Chen,
Jing Li,
Rui Xu,
Chao Jiang
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s233028
Subject(s) - cancer research , protein kinase b , biology , signal transduction , cancer , liver cancer , breast cancer , lactate dehydrogenase a , pi3k/akt/mtor pathway , hepatocellular carcinoma , medicine , lactate dehydrogenase , biochemistry , enzyme
Deubiquitinase OTU domain containing 4 (OTUD4) is initially identified as a K48-specific deubiquitinase and plays an important role in DNA damage repair signaling transduction. However, the expression level, prognostic role, biological function and mechanism of OTUD4 in multiple human cancers are unclear.