Open Access<p>Siva 1 Inhibits Cervical Cancer Progression and Its Clinical Prognosis Significance</p>
Author(s) -
Ting Liu,
Yihui Ma,
Zhong Lin Wang,
Wenjing Zhang,
Xinggang Yang
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s232994
Subject(s) - immunohistochemistry , cervical cancer , flow cytometry , apoptosis , medicine , ectopic expression , cancer research , cancer , oncology , pathology , biology , immunology , cell culture , biochemistry , genetics
Cervical cancer is the second most common female malignancies. But the exact etiology of cervical cancer is still under investigation. Recent observations revealed that the loss expression of Siva 1 was related to several different types of tumors. It could play an indispensable role in both exogenous and endogenous apoptotic signaling pathways. Nevertheless, the relationship between Siva 1 expression and cervical cancer progression has not yet been fully clarified. This study aimed to explore the functional role of Siva1 in cervical cancer.