Open Access<p>Heavy Water Affects Vital Parameters of Human Melanoma Cells in vitro</p>
Author(s) -
Johannes Kleemann,
Gabi Reichenbach,
Nadja Zöller,
Martin Jäger,
Roland Kaufmann,
Markus Meißner,
Stefan Kippenberger
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s230985
Subject(s) - apoptosis , melanoma , in vitro , cell cycle , chemistry , cell cycle checkpoint , deuterium , microtubule , cell growth , heavy water , cell , biophysics , microbiology and biotechnology , cancer research , biology , biochemistry , physics , quantum mechanics
Although regular water is composed of two hydrogens and one oxygen, referred to as H 2 O, a small amount of water on this planet contains alternative forms of elements with different molecular weights because of the addition of neutrons. The present study was dedicated to studying the effect of heavy water (D 2 O), in which the two hydrogens become substituted by deuterium, on the cell physiology of different human cells with particular focus on malignant melanoma cells.