Open Access<p>Downregulation of CDH16 in Papillary Thyroid Cancer and Its Potential Molecular Mechanism Analysed by qRT-PCR, TCGA and in silico Analysis</p>
Author(s) -
Pihong Li,
WU Qing,
Yihan Sun,
Xiaoyu Pan,
Yang Han,
Bing Yan,
Yinlong Zhang,
Jia Dong,
Zhouci Zheng
Publication year - 2019
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s229631
Subject(s) - thyroid cancer , carcinogenesis , downregulation and upregulation , papillary thyroid cancer , medicine , cancer research , metastasis , cancer , stage (stratigraphy) , in silico , clinical significance , thyroid , real time polymerase chain reaction , oncology , bioinformatics , pathology , gene , biology , genetics , paleontology
Thyroid cancer has the highest prevalence among the cancer types that affect the endocrine system; however, its molecular mechanisms are not yet determined. Cadherin-16 (CDH16) plays an important role in the tumorigenesis of human cancers, but its influence on papillary thyroid cancer (PTC) is poorly investigated. This study aimed to explore the role of CDH16 in PTC.