Open Access<p>Clinicopathological and Prognostic Significance of <em>EML4-ALK</em> Rearrangement in Patients with Surgically Resected Lung Adenocarcinoma: A Propensity Score Matching Study</p>
Author(s) -
Jun Shi,
Wenling Gu,
Yanfeng Zhao,
Junjie Zhu,
Gening Jiang,
Minwei Bao,
Jingyun Shi
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s229217
Subject(s) - anaplastic lymphoma kinase , medicine , adenocarcinoma , pathological , lung cancer , gastroenterology , oncology , ground glass opacity , fusion gene , gene rearrangement , stage (stratigraphy) , pathology , cancer , gene , malignant pleural effusion , biology , biochemistry , paleontology
The echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase ( EML4-ALK ) fusion gene is a key oncogenic driver in non-small cell lung cancer (NSCLC). This study analyzed the clinicopathological characteristics and prognostic significance of EML4-ALK fusion gene in patients with surgically resected adenocarcinoma.