Open Access<p>Downregulation of miR-216a-5p by long noncoding RNA PVT1 suppresses colorectal cancer progression via modulation of YBX1 expression</p>
Author(s) -
Xiang Zeng,
Yan Liu,
Huiping Zhu,
Di Chen,
Weimin Hu
Publication year - 2019
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s208983
Subject(s) - downregulation and upregulation , microrna , cancer research , competing endogenous rna , colorectal cancer , epithelial–mesenchymal transition , cell growth , pvt1 , metastasis , chemistry , long non coding rna , cancer , biology , medicine , gene , biochemistry
Increasing evidence has demonstrated that microRNAs (miRNAs) are closely related to the occurrence and development of tumors. MiR-216a-5p, located at 2p16.1, has been shown to suppress proliferation of cancerous cells. However, its expression and function in colorectal cancer (CRC) remain unclear.