Open Access<p>Cellular magnetic resonance imaging: in vivo tracking of gastric cancer cells and detecting of lymph node metastases using microparticles of iron oxide in mice</p>
Author(s) -
Jian Chen,
Gang Ren,
Rong Cai,
Xiangru Wu,
Ting Gui,
Jinmin Zhao,
Huali Li,
Cheng Guo
Publication year - 2019
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s206043
Subject(s) - in vivo , magnetic resonance imaging , lymph node , cancer , medicine , lymph , cancer research , pathology , chemistry , radiology , biology , microbiology and biotechnology
Monitoring the fate of implanted cells over time in an experimental animal may provide a new way to track the metastatic process. Lymph node metastase is of extremely importance for the prognostic prediction of gastric carcinoma. The aim of this study was to assess the feasibility of magnetic resonance imaging (MRI), using micron-sized superparamagnetic iron oxide particles (MPIO), for monitoring of the fate of gastric cancer cells and detecting the migration of gastric cancer cells through the lymphatic system in a mouse model.