Open Access<p>Forskolin exerts anticancer roles in non-Hodgkin’s lymphomas via regulating Axin/β-catenin signaling pathway</p>
Author(s) -
Hailei Wang,
Chunyan Lou,
Na Ma
Publication year - 2019
Publication title -
cancer management and research
Language(s) - Uncategorized
Resource type - Journals
ISSN - 1179-1322
DOI - 10.2147/cmar.s180754
Subject(s) - forskolin , cancer research , apoptosis , carcinogenesis , survivin , signal transduction , cell growth , wnt signaling pathway , protein kinase a , cell cycle , biology , chemistry , kinase , microbiology and biotechnology , cell culture , medicine , cancer , biochemistry , genetics
Non-Hodgkin's lymphomas (NHLs) account for 85% of lymphomas, which are characterized by high-degree malignancy, rapid progress, and even invasion into central nervous system in pediatric patients. Although the cure rate of pediatric NHL has improved, some patients have still underwent recurrence or death. This study focuses on the effects and mechanism of forskolin on the progression of NHL, aiming to find efficient therapy methods for pediatric NHL.