Open AccessPerinatal Mental Illness and Risk of Incident Autoimmune Disease: A Population-Based Propensity-Score Matched Cohort Study
Author(s) -
Hilary K. Brown,
Andrew S. Wilton,
Ning Liu,
Joel G. Ray,
CindyLee Dennis,
Simone Vigod
Publication year - 2021
Publication title -
clinical epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.868
H-Index - 58
ISSN - 1179-1349
DOI - 10.2147/clep.s344567
Subject(s) - medicine , mental illness , hazard ratio , disease , cohort , population , cohort study , propensity score matching , proportional hazards model , autoimmune disease , mental health , psychiatry , pediatrics , confidence interval , environmental health
Studies have demonstrated elevated risk for autoimmune disease associated with perinatal mental illness, but the extent to which this risk is specific to mental illness arising perinatally, and not mental illness generally, is unknown. Our objective was to compare the risk of autoimmune disease in women with mental illness arising within the perinatal period to (1) women with mental illness arising outside the perinatal period and (2) women who did not develop mental illness.