Open AccessIncidence of Atrial Fibrillation in Persons with Very High Serum Levels of N-Terminal Pro-B-Type Natriuretic Peptide: The Multi-Ethnic Study of Atherosclerosis
Author(s) -
Noel S. Weiss,
Esther Perez Trejo,
Richard A. Kronmal,
João A.C. Lima,
Susan R. Heckbert
Publication year - 2021
Publication title -
clinical epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.868
H-Index - 58
ISSN - 1179-1349
DOI - 10.2147/clep.s303560
Subject(s) - atrial fibrillation , medicine , incidence (geometry) , natriuretic peptide , cardiology , fibrillation , heart failure , physics , optics
While persons in the upper fourth or fifth of the distribution of serum levels of N-terminal pro-B type natriuretic peptide (NT-proBNP) are at a sharply increased risk of developing atrial fibrillation, their absolute risk of this condition (about 20 per 1000 per year) is not clearly high enough to justify prevention or early detection measures. We sought to determine whether the incidence of atrial fibrillation among persons with VERY high levels of NT-proBNP might be sufficiently high to warrant further action.