Open AccessPharmacogenetics of Anticoagulation and Clinical Events in Warfarin-Treated Patients: A Register-Based Cohort Study with Biobank Data and National Health Registries in Finland
Author(s) -
AnnaLeena Vuorinen,
Mika Lehto,
Mikko Niemi,
Kari Harno,
Juha Pajula,
Mark van Gils,
Jaakko Lähteenmäki
Publication year - 2021
Publication title -
clinical epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.868
H-Index - 58
ISSN - 1179-1349
DOI - 10.2147/clep.s289031
Subject(s) - medicine , warfarin , cohort , vkorc1 , incidence (geometry) , biobank , cyp2c9 , pharmacogenetics , adverse effect , pediatrics , genotype , atrial fibrillation , bioinformatics , physics , cytochrome p450 , metabolism , optics , biology , biochemistry , chemistry , gene
To assess the association between VKORC1 and CYP2C9 variants and the incidence of adverse drug reactions in warfarin-treated patients in a real-world setting.